Our paper focuses on the threats to the global development and sustainable economic development of a country that might include economic, political, human development, as well as sustainable development issues and problems. Sustainable economic development might serve as a tool for fostering the country’s prosperity and helping it to overcome various threats that might stem from its geolocation, economic situation, natural resources, as well as many other internal and external factors that all play their decisive roles. The paper uses a case study of the United States as an example of the country vulnerable to a plethora of threats. It analyzes the most crucial threats one by one and classifies the most notorious and impending issues stemming from these threats that might hamper the economic growth and development. In particular, we focus on the issue of energy security and the renewable energy sources (RES) that represent an important aspect in this debate and research. Our results can be used by the policymakers as well as regional development managers for improving the security strategy.