In order to compete in current international and local markets, organizations must find ways to reduce their cost. One of the reasons for the increased cost of organizations is employee absenteeism. The present study aimed to assess the impact of work overload, role ambiguity, and role conflict on job stress and absenteeism. The present study also explored the mediating impact of stress among mentioned independent variables and absenteeism. The data of the study was collected from the employees working conducted electronic goods-producing firms of Indonesia through convenience sampling. The findings of the study confirmed all proposed hypothesis. The findings of the study fill the gap of few studies tried to identify the role of different factors, creating stress and causing absenteeism among employees of the manufacturing sector of Indonesia. The results of the research are helpful for the policymakers of the sector and HR managers to device policies by which they can engage the employees.