Ensuring security is one of the main functions of the state, therefore, in that area one has to deal with a wide range of threats and challenges. In the analysis of the changing security environment issues in the 21st century, it is reasonable to look at historical events and to do appropriate case studies. Lithuania in the interwar period can be considered as a very valuable case in the context of the analysis of threats to national security. Over two decades, Lithuania acquired the experience of the conventional warfare, encountered analogues of little green men, and went through military coups, civil unrest, and the consequences of economic sanctions (economic warfare); it was exposed to external intelligence and agents of influence of other states operating underground who spread subversive rumours and distributed underground newspapers and leaflets. The present paper focuses on the range of those issues.