The article analyses the realization of the support from the EU structural funds in the regions of Lithuania. It has been investigated, in which areas and regions the funds have been most and least successfully assimilated. Socio-economic development of the Lithuanian regions has been analysed in the period of 2008-2011 and the influence of the assimilated EU support. Similarly, debatable questions of the region, its development and conception of regional politics have been studied.Statistical data from Eurostat, the Department of Statistics of Lithuania under the Government of the Republic of Lithuania and the Ministry of Finance of the Republic of Lithuania have been used in the research.