The article is dedicated to the research of legal and management aspects of intellectual property rights protection in the field of medicine and biotechnologies. The authors clarified the patenting peculiarities of inventions in the area of medicine and biotechnologies, particularly issues concerning applications for obtaining patents, the determination of intellectual property compliance with patentability requirements, the registration of granted patents in the relevant registry etc. They identified the legal and organizational aspects of intellectual property rights protection in the field of medicine and biotechnologies upon the study of the leading European countries experience (using the examples of the United Kingdom, Germany and France). One summarized the international experience in the protection of intellectual property rights in the field of medicine and biotechnologies and highlighted the regulation specifics of these issues according to the current Ukrainian legislation. In particular, the authors defined the requirements for the protection of intellectual property rights in the field of medicine and biotechnologies, which have been set out in legal documents at the international level. Recommendations for management organization and intellectual brand capital protection depending on specificity of national economic and legal model. Are offered. The mechanism of economic security management of a country for intellectual property right protection in the field of medicine and biotechnologies is created.