An important strategic goal of the infrastructure development in the Czech Republic is the use of modern detection, diagnostic, information, control and security technologies based on intelligent transport systems (ITS), global navigation satellite systems and Earth observation systems. The modern transport system is based on a multimodal and intermodal approach. The individual modes of transport are being developed to form a coherent whole from the users’ point of view. Transport infrastructure and vehicles must be in good technical condition and equipped with intelligent technologies. Managing the process of transporting people and goods requires reliable transmission of information in real time. The transport system must also be operated in a secure manner, be prepared for risk and emergencies and have the ability to deal with security threats arising from illegal behaviour. The paper briefly shows the process of building ITS, the possibilities of using modern intelligent information, diagnostic, control and safety technologies in transport until 2027 with a view to 2050.