A set of criteria has been substantiated for evaluating the effectiveness of the implementation of the functions of the mechanism for ensuring the leadership effectiveness of the managerial staff of enterprises. The set gives a chance to make a comprehensive evaluation of the integral indicator of human resource management. This makes it possible to determine the effectiveness level of human resource management. The study carried out allowed to propose a functional and structural approach that includes the following functions: analysis and planning of personnel, recruitment and selection of personnel, attestation and evaluation of personnel, organization of labor relations, motivational support, creation of working conditions, information provision, development and training of personnel. Under uncertainty, its application makes it possible to evaluate the impact of the effectiveness of the human resource management on the level of productivity of the studied enterprises.